Viagra Pharmacy: Snoring

Snoring is sound generated from the upper airway due to vibration of the uvula and soft palate. It occurs during inspiration, and rarely in expiration. Snoring is associated with changes in the caliber of the upper airway, which reduces flow and increases airway resistance. These changes may not be significant enough to produce clinical symptoms or create disruption in sleep. Snoring under these circumstances is termed primary snoring. When it occurs in conjunction with disordered sleep, it may be associated with symptoms that range from daytime sleepiness to severe OSAS with nocturnal hypoxemia and multiple cardiovascular effects.

Snoring and OSAS are thought to represent opposite ends of a continuum of SDB; however, snoring may actually represent a distinct comorbidity. Support for this concept is found in the characterization of sleep-related breathing disorders with clinically significant symptoms that occur in the absence of snoring. To date, there has been no study that conclusively demonstrates an evolution from snoring to OSAS. Also, studies have shown improvement in snoring but not OSAS following upper airway surgery. These combined factors lend weight to the concept of snoring as a discrete condition, which may have additive or synergistic effects on SDB.

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UARS

The UARS is characterized by sleep-related flow limitation and increases in upper airway resistance that precipitates arousals resulting in fragmented sleep and EDS. By definition, these alterations occur without apneas or desaturations. This term was first applied to patients who had EDS defined by a shortened mean sleep latency on a multiple sleep latency test, without clear cause documented by overnight polysomnography. These patients were assumed to have idiopathic hypersomnia. Utilizing “invasive polysomnography” with an esophageal pressure (Pes) transducer and full-face pneumotachograph increased upper airway resistance as demonstrated by increasingly negative inspiratory Pes in conjunction with reduced oral/nasal airflow.